Pharmaceutical research and discovery from Pharma Journal: target identification, preclinical science, drug-development platforms and the laboratories advancing new therapies. The science and strategy behind the industry's pipeline, for professionals across biotech, pharma and academia.
A familiar antibiotic has crossed an ocean with an unfamiliar name. In April 2024 the U.S. Food and Drug Administration approved Pivya pivmecillinam for uncomplicated urinary tract infection in adult
By Dr. Eleanor Vance, Regulatory Affairs Editor
Five years after the acute waves of COVID-19, Long COVID has settled into public health planning as a common post-infectious condition with sustained clinical, economic and social effects. The term de
By Dr. Eleanor Vance, Regulatory Affairs Editor
Nitazenes are highly potent synthetic opioids from the benzimidazole family that now present a fast-moving threat in the United Kingdom and in other regions. The core scaffold places them apart from n
By Dr. Eleanor Vance, Regulatory Affairs Editor
Public attention to nicotinamide mononucleotide has grown quickly as evidence about NAD+ biology has entered mainstream discussion. Early animal data suggested broad benefits across metabolic and vasc
By Dr. Eleanor Vance, Regulatory Affairs Editor
Cellular ageing is not a single event but a convergence of gradual molecular failures that accumulate over time. The recognised hallmarks include telomere attrition, genomic instability from DNA damag
By Dr. Eleanor Vance, Regulatory Affairs Editor
Molecular biology studies how DNA, RNA and proteins control the behaviour of cells. It asks how genetic information is stored, copied, transcribed and translated, then traces how those molecular instr
By Dr. Eleanor Vance, Regulatory Affairs Editor
The idea that a single infusion of a patient's own immune cells could clear aggressive cancer once seemed like daring fiction. CAR T‑cell therapy has turned that notion into clinical fact, standing sh
By Dr. Eleanor Vance, Regulatory Affairs Editor
The hot flush that wakes you at 03:00, the sudden fog that steals a board‑room sentence, the invisible shift that hollows bones – the menopausal transition is blunt. Yet for many, relief sits in plain
By Dr. Eleanor Vance, Regulatory Affairs Editor
Humanity is standing at the threshold of a reproductive revolution. In laboratories from Kyoto to Cambridge, scientists are taking ordinary skin or blood cells, rewinding their biological clocks, and
By Dr. Eleanor Vance, Regulatory Affairs Editor
The queue outside a London GP surgery on a brisk winter morning tells a familiar story: patients waiting for lab results that determine whether they face a viral infection, cancer scare, or routine ch
By Dr. Eleanor Vance, Regulatory Affairs Editor
The promise of longer, healthier living has long been tied to cellular science. At the heart of this pursuit lies a small yet powerful molecule — Nicotinamide Mononucleotide (NMN). Closely related to
By Dr. Eleanor Vance, Regulatory Affairs Editor
Pain, for many, is a deeply personal and often silent struggle. Whether it stems from surgery, chronic illness, or everyday injuries, effective relief is essential. For those turning to codeine phosph
By Priya Raghavan, Biotech & Markets Analyst
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