News13 July 2026· 9 min read
JAK1 Inhibitor Selectivity and What It Means for Prescribers
The Janus kinase family comprises four intracellular tyrosine kinases JAK1, JAK2, JAK3, and TYK2 that transduce signals from a broad range of cytokine receptors to downstream transcription factors, principally the signal transducer and activator of transcription (STAT) proteins.…
By Dr. Eleanor Vance, Regulatory Affairs Editor