Led by Liverpool School of Tropical Medicine and embedded within the North West of England, iiCON (Infection Innovation Consortium) is an open-innovation programme that brings together academic, industry and public-sector partners to accelerate the discovery and development of solutions to infectious disease. Partners include Unilever, LifeArc and Medicines for Malaria Venture, reflecting the consortium's reach across consumer health, life sciences investment and global disease control.
The programme operates across eleven distinct research and development platforms, spanning the full pipeline from early-stage bioactive discovery to clinical evaluation. The Bioactives Library supports the identification of novel antimicrobial agents, while the Hits to Leads platform progresses promising compounds towards new antibiotic candidates. Organoid modelling and advanced AMR modelling platforms underpin mechanistic drug discovery and resistance research, and a dedicated Human Challenge platform enables small-scale clinical trials in a controlled setting.
Diagnostic development sits at the heart of iiCON's translational work. Published case studies document progress on a sputum-free diagnostic for tuberculosis, a scalable test for avian influenza, and a rapid test for antimicrobial resistance, all developed through the consortium's open-innovation microbiome ecosystem model. Further platforms address randomised controlled trials, mapping and modelling, nanotherapeutics, antibody humanisation, and long-acting therapeutics, giving the consortium a broad capability base across the infectious disease space.
A dedicated technology arm, iiTECH, extends this work into applied sensing and quality assurance, with demonstrated projects including lymphatic filariasis sensors and indoor residual spraying quality assurance tools deployed across Africa and India.
Further information is available at infectioninnovation.com.