Cellular rejuvenation and tissue repair
Cellular ageing is not a single event but a convergence of gradual molecular failures that accumulate over time. The recognised hallmarks include telomere attrition, genomic instability from DNA damage, epigenetic alterations, mitochondrial dysfunction, loss of proteostasis, and the build-up of senescent cells. These mechanisms together erode the regenerative capacity of tissues and increase susceptibility to […]